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Sigma
Tributylphosphine solution
T7567 -
200 mM (in N-methyl-2-pyrrolidinone), liquid
DOWNLOAD MSDS (PDF) Synonym: TBP
CAS Number: 998-40-3
Empirical Formula (Hill Notation): C12H27P
Molecular Weight: 202.32
MDL number: MFCD00009462
PubChem Substance ID: 24900459
Properties
| Related Categories | Cell Lysis and Protein Extraction Reagents, Chemical Modification Reagents, Native Protein Sample Preparation, Protein Modification, Reagents for reduction of proteins, |
| form | liquid |
| concentration | 200 mM (in N-methyl-2-pyrrolidinone) |
Description
Application
TBP is an uncharged reducing agent for disulfide bonds of cysteine residues. This reagent is ideally suited for preparation of protein samples prior to IEF and 2D electrophoresis. Reduction with TBP and subsequent alkylation with iodoacetamide improves resolution, allows greater sample loads, and therefore, improves visualization of low abundance proteins
Packaging
Sealed ampule of 0.5 mL
Price and Availability
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Documents
Certificate of Analysis
| T7567 - Bulletin (26 KB) |
| Proteomics Prod Guide (394 KB ) |
| Technical Article Jan03 (199 KB ) |
| FT-IR Condensed Phase |  |
| FT-IR Raman | |
| FT-NMR |  |
| Structure Search |  |
| Similar Products |
Safety Information
| Symbol |     GHS02, GHS05, GHS07, GHS08 |
| Signal word | Danger |
| Hazard statements | H250-H314-H335-H360D |
| Precautionary statements | P201-P222-P231-P261-P280-P422 |
| Personal Protective Equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi |
| Risk Statements | 36/38 |
| Safety Statements | 41 |
| WGK Germany | 3 |
| Flash Point(F) | 186.8 °F |
| Flash Point(C) | 86 °C |
Technical information & documentation associated with this product is available in the Safety & Documentation tab.
References
Phongpa-Ngan, P., et al., Proteomic Analysis and Differential Expression in Protein Extracted from Chicken with a Varying Growth Rate and Water-Holding Capacity. J. Agric. Food Chem. 59(24), 13181-13187, (2011)
Herbert, B., et al., Reduction and alkylation of proteins in preparation of two dimensional map analysis: why, when, and how?. Electrophoresis 22, 2046-57, (2001)
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